Privo is looking for patients with oral cancer (T1-T2) to participate in its ongoing study

For information regarding this trial, please visit
PRV111 consists of a topical patch designed to deliver and retain high concentrations of chemotherapy agent within the primary tumor and associated lymph nodes. When placed on a tumor, PRV111 releases and retains cisplatin-loaded particles into the tumor, resulting in a dramatic reduction in tumor size, without the accompanying systemic side effects associated with intravenous cisplatin (i.e. nephrotoxicity and neurotoxicity). This has been seen in several preclinical studies. Local and regional effects of PRV111 are expected to improve tumor resectability, decrease post-operative radiation and chemotherapy, and improve patient survival. This organ-sparing therapy is special because it can preserve the oral cavity form and function. Also, it can improve control of the disease loco-regionally, which can result in improving a patient’s overall survival rate. In patients with metastatic disease, PRV111 (when combined with standard of care chemo-radiation regimen) can provide improved locoregional control while maintaining a tolerable side effect profile that ultimately improves the quality of life. Before you consent to join a clinical trial, it is important for you to have all the information you need to be confident about your decision.
If you have any questions, please contact us by filling up the following form:

Participating Hospitals

UT Health, University of Texas Science Center, Houston, TX 77030

Baylor Clinic, 6620 Main Street, Houston, TX 77030

Baylor St. Luke’s Medical Center, 6720 Bertner Avenue, Houston, TX  77030

Baylor College of Medicine, 1 Baylor Plaza, Houston, TX  77030

Houston Methodist Hospital, 6550 Fannin Street, Suite 1701, Houston, TX  77030

Ben Taub Hospital, 1504 Ben Taub Loop, Houston, TX  77030

Harris Health System – Smith Clinic, 2525A Holly Hall Street, Houston, TX  77054

Memorial Hermann-Texas Medical Center, Houston, TX  77030

University of Cincinnati, Head & Neck Cancer Center, 234 Goodman Street, Cincinnati, OH  45219 

West Chester Hospital, 7700 University Drive, West Chester, OH 45069